Spatial Transcriptomic Technologies

Spatial transcriptomic technologies enable measurement of expression levels genes systematically throughout tissue space, deepening our understanding cellular organizations and interactions within tissues as well illuminating biological insights in neuroscience, developmental biology a range diseases, including cancer. A variety spatial have been developed and/or commercialized, differing resolution, sensitivity, multiplexing capability, throughput coverage. In this paper, we review key enabling their applications the perspective techniques new emerging that are to address current limitations methodologies. addition, describe how transcriptomics data can be integrated with other omics modalities, complementing methods deciphering cellar phenotypes providing novel insight into organization.